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Peripheral edema: There are several reports of peripheral edema Other: Other adverse reactions reported following morphine therapy include depression of cough reflex, interference with thermal regulation, peripheral edema. Like all beta-lactam antibiotics, cefotaxime’s ability to interfere with PBP-mediated cell wall synthesis ultimately leads to cell lysis. About one in twenty (six per cent) of women will still get pregnant when using Depo Provera; this is very low compared with other methods www.farmaciasinreceta.org. Interferon Alfa-2a: (Minor) An increased risk of bleeding may occur when NSAIDs, such as diclofenac, are used with agents that cause clinically significant thrombocytopenia, such as myelosuppressive antineoplastic agents.